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Vax1/2 Genes Counteract Mitf-Induced Respecification of the Retinal Pigment Epithelium

During vertebrate eye development, the transcription factor MITF acts to promote the development of the retinal pigment epithelium (RPE). In embryos with Mitf mutations, the future RPE hyperproliferates and is respecified as retinal tissue but only in a small portion of the dorsal RPE. Using a serie...

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Detalhes bibliográficos
Main Authors: Ou, Jingxing, Bharti, Kapil, Nodari, Alessandro, Bertuzzi, Stefano, Arnheiter, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598659/
https://ncbi.nlm.nih.gov/pubmed/23555005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059247
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