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Vax1/2 Genes Counteract Mitf-Induced Respecification of the Retinal Pigment Epithelium
During vertebrate eye development, the transcription factor MITF acts to promote the development of the retinal pigment epithelium (RPE). In embryos with Mitf mutations, the future RPE hyperproliferates and is respecified as retinal tissue but only in a small portion of the dorsal RPE. Using a serie...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3598659/ https://ncbi.nlm.nih.gov/pubmed/23555005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059247 |
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