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Vax1/2 Genes Counteract Mitf-Induced Respecification of the Retinal Pigment Epithelium

During vertebrate eye development, the transcription factor MITF acts to promote the development of the retinal pigment epithelium (RPE). In embryos with Mitf mutations, the future RPE hyperproliferates and is respecified as retinal tissue but only in a small portion of the dorsal RPE. Using a serie...

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Bibliografiske detaljer
Main Authors: Ou, Jingxing, Bharti, Kapil, Nodari, Alessandro, Bertuzzi, Stefano, Arnheiter, Heinz
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598659/
https://ncbi.nlm.nih.gov/pubmed/23555005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059247
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