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In vivo VL-targeted microbial superantigen induced global shifts in the B-cell repertoire
To subvert host defenses, some microbial pathogens produce proteins that interact with conserved motifs in variable regions of B-cell antigen receptor shared by large sets of lymphocytes, which define the properties of a superantigen. As the clonal composition of the lymphocyte pool is a major deter...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3598568/ https://ncbi.nlm.nih.gov/pubmed/22696444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200245 |
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