Attenuated antigen-specific T cell responses in cirrhosis are accompanied by elevated serum interleukin-10 levels and down-regulation of HLA-DR on monocytes

BACKGROUND: Advanced liver disease predisposes to bacterial translocation and endotoxaemia which can contribute to elevated circulating levels of IL-10 and down-regulation of MHC class II on antigen-presenting cells. We sought to evaluate antigen-specific T-cell responses toward common viral antigen...

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Bibliografiske detaljer
Main Authors: Peter, Jack, Frey, Oliver, Stallmach, Andreas, Bruns, Tony
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598528/
https://ncbi.nlm.nih.gov/pubmed/23446058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-13-37
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