Structural and functional brain connectivity in presymptomatic familial frontotemporal dementia

OBJECTIVE: We aimed to investigate whether cognitive deficits and structural and functional connectivity changes can be detected before symptom onset in a large cohort of carriers of microtubule-associated protein tau and progranulin mutations. METHODS: In this case-control study, 75 healthy individ...

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Autors principals: Dopper, Elise G.P., Rombouts, Serge A.R.B., Jiskoot, Lize C., den Heijer, Tom, de Graaf, J. Roos A., de Koning, Inge, Hammerschlag, Anke R., Seelaar, Harro, Seeley, William W., Veer, Ilya M., van Buchem, Mark A., Rizzu, Patrizia, van Swieten, John C.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598452/
https://ncbi.nlm.nih.gov/pubmed/23390180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e31828407bc
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