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Negative regulation of immunoglobulin kappa light-chain gene transcription by a short sequence homologous to the murine B1 repetitive element.

B-cell-specific expression of the immunoglobulin kappa light-chain (Ig kappa) gene is in part accomplished by negative regulatory influences. Here we describe a new negatively acting element (termed kappa NE) immediately upstream of the NF-kappa B-binding site in the Ig kappa intronic enhancer. The...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Saksela, K, Baltimore, D
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359843/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8497276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3698-3705.1993
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