A conserved C-terminal sequence that is deleted in v-ErbA is essential for the biological activities of c-ErbA (the thyroid hormone receptor).

The thyroid hormone (T3) receptor type alpha, the c-ErbA alpha proto-oncoprotein, stimulates transcription of T3-dependent promoters, interferes with AP-1 activity, and induces erythroid differentiation in a ligand-dependent manner. The v-ErbA oncoprotein does not bind hormone and has lost all of th...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Saatcioglu, F, Bartunek, P, Deng, T, Zenke, M, Karin, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8098843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3675-3685.1993
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