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GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.

Phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2 alpha) by the protein kinase GCN2 mediates increased translation of the transcriptional activator GCN4 in amino acid-starved yeast cells. We show that this key phosphorylation event and the attendant translatio...

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Marton, M J, Crouch, D, Hinnebusch, A G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1993
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359824/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8497269/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3541-3556.1993
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