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TAP1, a yeast gene that activates the expression of a tRNA gene with a defective internal promoter.

We developed a genetic selection system based on nonsense suppression in Saccharomyces cerevisiae to identify mutations in proteins involved in transcription initiation by RNA polymerase III. A SUP4 tRNA(Tyr) internal promoter mutation (A53T61) that was unable to suppress ochre mutations in vivo and...

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Detalhes bibliográficos
Main Authors: Di Segni, G, McConaughy, B L, Shapiro, R A, Aldrich, T L, Hall, B D
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC359811/
https://ncbi.nlm.nih.gov/pubmed/8497259
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