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Current status of drug screening and disease modelling in human pluripotent stem cells

The emphasis in human pluripotent stem cell (hPSC) technologies has shifted from cell therapy to in vitro disease modelling and drug screening. This review examines why this shift has occurred, and how current technological limitations might be overcome to fully realise the potential of hPSCs. Detai...

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Autors principals: Rajamohan, Divya, Matsa, Elena, Kalra, Spandan, Crutchley, James, Patel, Asha, George, Vinoj, Denning, Chris
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597971/
https://ncbi.nlm.nih.gov/pubmed/22886688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200053
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