MicroRNA-92a Negatively Regulates Toll-like Receptor (TLR)-triggered Inflammatory Response in Macrophages by Targeting MKK4 Kinase

Toll-like receptors (TLRs) play a critical role in the initiation of immune responses against invading pathogens. MicroRNAs have been shown to be important regulators of TLR signaling. In this study, we have found that the stimulation of multiple TLRs rapidly reduced the levels of microRNA-92a (miRN...

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Detalhes bibliográficos
Main Authors: Lai, Lihua, Song, Yinjing, Liu, Yang, Chen, Qingyun, Han, Quan, Chen, Weilin, Pan, Ting, Zhang, Yuanyuan, Cao, Xuetao, Wang, Qingqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597832/
https://ncbi.nlm.nih.gov/pubmed/23355465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445429
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