MicroRNA-92a Negatively Regulates Toll-like Receptor (TLR)-triggered Inflammatory Response in Macrophages by Targeting MKK4 Kinase

Toll-like receptors (TLRs) play a critical role in the initiation of immune responses against invading pathogens. MicroRNAs have been shown to be important regulators of TLR signaling. In this study, we have found that the stimulation of multiple TLRs rapidly reduced the levels of microRNA-92a (miRN...

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Bibliographische Detailangaben
Hauptverfasser: Lai, Lihua, Song, Yinjing, Liu, Yang, Chen, Qingyun, Han, Quan, Chen, Weilin, Pan, Ting, Zhang, Yuanyuan, Cao, Xuetao, Wang, Qingqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597832/
https://ncbi.nlm.nih.gov/pubmed/23355465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445429
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