Glucagon Regulation of Oxidative Phosphorylation Requires an Increase in Matrix Adenine Nucleotide Content through Ca(2+) Activation of the Mitochondrial ATP-Mg/P(i) Carrier SCaMC-3

It has been known for a long time that mitochondria isolated from hepatocytes treated with glucagon or Ca(2+)-mobilizing agents such as phenylephrine show an increase in their adenine nucleotide (AdN) content, respiratory activity, and calcium retention capacity (CRC). Here, we have studied the role...

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Detalhes bibliográficos
Main Authors: Amigo, Ignacio, Traba, Javier, González-Barroso, M. Mar, Rueda, Carlos B., Fernández, Margarita, Rial, Eduardo, Sánchez, Aránzazu, Satrústegui, Jorgina, del Arco, Araceli
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Bioenergetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597818/
https://ncbi.nlm.nih.gov/pubmed/23344948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409144
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