Evidence for possible non-canonical pathway(s) driven early-onset colorectal cancer in India

Two genetic instability pathways viz. chromosomal instability, driven primarily by APC mutation induced deregulated Wnt signaling, and microsatellite instability (MSI) caused by mismatch repair (MMR) inactivation, together account for greater than 90% of late-onset colorectal cancer. Our understandi...

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Detalhes bibliográficos
Principais autores: Raman, Ratheesh, Kotapalli, Viswakalyan, Adduri, Raju, Gowrishankar, Swarnalata, Bashyam, Leena, Chaudhary, Ajay, Vamsy, Mohana, Patnaik, Sujith, Srinivasulu, Mukta, Sastry, Regulagadda, Rao, Subramanyeshwar, Vasala, Anjayneyulu, Kalidindi, NarasimhaRaju, Pollack, Jonathan, Murthy, Sudha, Bashyam, Murali
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597761/
https://ncbi.nlm.nih.gov/pubmed/23168910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21976
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