Distinct gene expression profiles of viral- and non-viral associated Merkel cell carcinoma revealed by transcriptome analysis

Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine tumor with high mortality rates. Merkel cell polyomavirus (MCPyV), identified in the majority of MCC, may drive tumorigenesis via viral T antigens. However, mechanisms underlying pathogenesis in MCPyV-negative MCC remain poorly un...

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Autors principals: Harms, Paul William, Patel, Rajiv Michael, Verhaegen, Monique Elise, Giordano, Thomas James, Nash, Kevin Tyler, Johnson, Craig Norman, Daignault, Stephanie, Thomas, Dafydd Gareth, Gudjonsson, Johann Eli, Elder, James Tilford, Dlugosz, Andrzej Antoni, Johnson, Timothy M., Fullen, Douglas Randall, Bichakjian, Christopher Keram
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597750/
https://ncbi.nlm.nih.gov/pubmed/23223137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.445
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