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The 5'-flanking region of the mouse thymidylate synthase gene is necessary but not sufficient for normal regulation in growth-stimulated cells.

The thymidylate synthase (TS) gene is a housekeeping gene that is expressed at much higher levels in proliferating cells than in quiescent cells. We have studied the role of the TS 5'-flanking sequences in regulating the level of expression of the mouse TS gene. A variety of chimeric TS minigenes th...

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Li, Y, Li, D, Osborn, K, Johnson, L F
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359772/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1990264/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.2.1023-1029.1991
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