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Validation of an entirely in vitro approach for rapid prototyping of DNA regulatory elements for synthetic biology

A bottleneck in our capacity to rationally and predictably engineer biological systems is the limited number of well-characterized genetic elements from which to build. Current characterization methods are tied to measurements in living systems, the transformation and culturing of which are inherent...

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Autori principali: Chappell, James, Jensen, Kirsten, Freemont, Paul S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597704/
https://ncbi.nlm.nih.gov/pubmed/23371936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt052
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