Microstructural White Matter Changes, Not Hippocampal Atrophy, Detect Early Amnestic Mild Cognitive Impairment

BACKGROUND: Alzheimer’s disease (AD) is generally considered to be characterized by pathology in gray matter of the brain, but convergent evidence suggests that white matter degradation also plays a vital role in its pathogenesis. The evolution of white matter deterioration and its relationship with...

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Detalhes bibliográficos
Main Authors: Zhuang, Lin, Sachdev, Perminder S., Trollor, Julian N., Reppermund, Simone, Kochan, Nicole A., Brodaty, Henry, Wen, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597581/
https://ncbi.nlm.nih.gov/pubmed/23516569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058887
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