Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability

UPF1 eliminates aberrant mRNAs harboring premature termination codons, and regulates the steady-state levels of normal physiological mRNAs. Although genome-wide studies of UPF1 targets performed, previous studies did not distinguish indirect UPF1 targets because they could not determine UPF1-depende...

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Autors principals: Tani, Hidenori, Imamachi, Naoto, Salam, Kazi Abdus, Mizutani, Rena, Ijiri, Kenichi, Irie, Takuma, Yada, Tetsushi, Suzuki, Yutaka, Akimitsu, Nobuyoshi
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597577/
https://ncbi.nlm.nih.gov/pubmed/23064114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.22360
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