1,25-Dihydroxyvitamin D3 Suppresses TLR8 Expression and TLR8-Mediated Inflammatory Responses in Monocytes In Vitro and Experimental Autoimmune Encephalomyelitis In Vivo

1,25-Dihydroxyvitamin D3 (1,25(OH)(2)D(3)) suppresses autoimmunity and inflammation; however, the mechanism of its action has not been fully understood. We sought in this study to determine whether the anti-immune/anti-inflammatory action of 1,25(OH)(2)D(3) is in part mediated through an interplay b...

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Detalhes bibliográficos
Main Authors: Li, Bo, Baylink, David J., Deb, Chandra, Zannetti, Claudia, Rajaallah, Fatima, Xing, Weirong, Walter, Michael H., Lau, K.-H. William, Qin, Xuezhong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597563/
https://ncbi.nlm.nih.gov/pubmed/23516559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058808
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