The combination of an oxygen-dependent degradation domain-regulated adenovirus expressing the chemokine RANTES/CCL5 and NK-92 cells exerts enhanced antitumor activity in hepatocellular carcinoma

Oncolytic adenoviruses are modified based on adenovirus serotype 5 (Ad5), which belongs to subgroup C and depends on Coxsackie-adenovirus receptor (CAR) to recognize target cells. However, expression of CAR is generally low or lost in certain tumors including hepatocellular carcinoma (HCC). By contr...

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Hlavní autoři: LI, JIANG, LIU, HUI, LI, LINFANG, WU, HONGPING, WANG, CHUNHONG, YAN, ZI, WANG, YING, SU, CHANGQING, JIN, HUAJUN, ZHOU, FUPING, WU, MENGCHAO, QIAN, QIJUN
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597539/
https://ncbi.nlm.nih.gov/pubmed/23292657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.2217
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