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Spatial Pattern Dynamics of 3D Stem Cell Loss of Pluripotency via Rules-Based Computational Modeling

Pluripotent embryonic stem cells (ESCs) have the unique ability to differentiate into cells from all germ lineages, making them a potentially robust cell source for regenerative medicine therapies, but difficulties in predicting and controlling ESC differentiation currently limit the development of...

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Détails bibliographiques
Auteurs principaux: White, Douglas E., Kinney, Melissa A., McDevitt, Todd C., Kemp, Melissa L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597536/
https://ncbi.nlm.nih.gov/pubmed/23516345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002952
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