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A 5'-3' exonuclease from Saccharomyces cerevisiae is required for in vitro recombination between linear DNA molecules with overlapping homology.

When two linear DNA molecules with overlapping, homologous ends were incubated with a yeast nuclear extract, they recombined at the region of homology to produce a joint molecule. We have identified a 5'-3' exonuclease in the extract that is likely to be responsible for the formation of the observed...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Huang, K N, Symington, L S
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359747/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8388534/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3125-3134.1993
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