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Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

In Saccharomyces cerevisiae, the GTP-binding Ypt1 protein (Ypt1p) is essential for endoplasmic reticulum-to-Golgi protein transport. By exploiting a GAL10-YPT1 fusion to regulate YPT1 expression, three multicopy suppressors, SLY2, SLY12, and SLY41, and a single-copy suppressor, SLY1-20, that allowed...

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Publicado en:Mol Cell Biol
Autores principales: Dascher, C, Ossig, R, Gallwitz, D, Schmitt, H D
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1991
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359739/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1990290/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.2.872
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