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Suppressor analysis of temperature-sensitive RNA polymerase I mutations in Saccharomyces cerevisiae: suppression of mutations in a zinc-binding motif by transposed mutant genes.

Starting with two temperature-sensitive mutants (rpa190-1 and rpa190-5) of Saccharomyces cerevisiae, both of which are amino acid substitutions in the putative zinc-binding domain of the largest subunit (A190) of RNA polymerase I, we have isolated many independent pseudorevertants carrying extrageni...

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Publicat a:Mol Cell Biol
Autors principals: McCusker, J H, Yamagishi, M, Kolb, J M, Nomura, M
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359726/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846671/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.2.746-753.1991
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