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A mutation in Drosophila Aldolase causes temperature-sensitive paralysis, shortened lifespan, and neurodegeneration
We describe the characterization of m4, an autosomal recessive, temperature-sensitive paralytic mutant in Drosophila that is associated with shortened lifespan and neurodegeneration. Deletion mapping places the mutation in the gene encoding the glycolytic enzyme, Aldolase. The mutant enzyme contains...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597222/ https://ncbi.nlm.nih.gov/pubmed/22882183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01677063.2012.706346 |
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