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FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse

The emergence of pluripotent epiblast (EPI) and primitive endoderm (PrE) lineages within the inner cell mass (ICM) of the mouse blastocyst involves initial co-expression of lineage-associated markers followed by mutual exclusion and salt-and-pepper distribution of lineage-biased cells. Precisely how...

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Detalhes bibliográficos
Main Authors: Kang, Minjung, Piliszek, Anna, Artus, Jérôme, Hadjantonakis, Anna-Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597205/
https://ncbi.nlm.nih.gov/pubmed/23193166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.084996
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