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Disruption and Destabilization of Meibomian Lipid Films Caused by Increasing Amounts of Ceramides and Cholesterol

PURPOSE. We evaluated quantitatively direct effects of ceramide (Cer) and free cholesterol (FC) on meibomian lipid films (MLF) using a Langmuir trough (LT) and a Brewster angle microscope (BAM). METHODS. Meibum was obtained from healthy volunteers. A series of mixtures of meibum with Cer or FC (mixe...

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Hauptverfasser: Arciniega, Juan C., Uchiyama, Eduardo, Butovich, Igor A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597190/
https://ncbi.nlm.nih.gov/pubmed/23341008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10662
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