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Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase.

Saccharomyces cerevisiae strains that contain the ery8-1 mutation are temperature sensitive for growth due to a defect in phosphomevalonate kinase, an enzyme of isoprene and ergosterol biosynthesis. A plasmid bearing the yeast ERG8 gene was isolated from a YCp50 genomic library by functional complem...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Tsay, Y H, Robinson, G W
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359713/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.2.620
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