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Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes.

A full-length cDNA clone for the mouse mdr1 gene can confer multidrug resistance when introduced by transfection into otherwise drug-sensitive cells. In the same assay, a full-length cDNA clone for a closely related member of the mouse mdr gene family, mdr2, fails to confer multidrug resistance. To...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Buschman, E, Gros, P
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1990275/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.2.595
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