Loss of MMP-2 in murine osteoblasts upregulates osteopontin and bone sialoprotein expression in a circuit regulating bone homeostasis

Multicentric osteolysis with arthropathy (MOA; MIM 605156) is an inherited osteolyses and arthritis syndrome resulting from loss of matrix metalloproteinase 2 (MMP-2). We recently demonstrated that Mmp2(–/–) mice represent a unique model for the study of the human disease, sharing many features of t...

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Bibliographic Details
Main Authors: Mosig, Rebecca A., Martignetti, John A.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Limited 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597021/
https://ncbi.nlm.nih.gov/pubmed/22917927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007914
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