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Loss of MMP-2 in murine osteoblasts upregulates osteopontin and bone sialoprotein expression in a circuit regulating bone homeostasis
Multicentric osteolysis with arthropathy (MOA; MIM 605156) is an inherited osteolyses and arthritis syndrome resulting from loss of matrix metalloproteinase 2 (MMP-2). We recently demonstrated that Mmp2(–/–) mice represent a unique model for the study of the human disease, sharing many features of t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597021/ https://ncbi.nlm.nih.gov/pubmed/22917927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007914 |
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