TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3

Although it is known that tumor necrosis factor receptor (TNFR) signaling plays a crucial role in vascular integrity and homeostasis, the contribution of each receptor to these processes and the signaling pathway involved are still largely unknown. Here, we show that targeted gene knockdown of TNFRS...

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Detalhes bibliográficos
Main Authors: Espín, Raquel, Roca, Francisco J., Candel, Sergio, Sepulcre, María P., González-Rosa, Juan M., Alcaraz-Pérez, Francisca, Meseguer, José, Cayuela, María L., Mercader, Nadia, Mulero, Victoriano
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597020/
https://ncbi.nlm.nih.gov/pubmed/22956347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010249
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