Aqueous Extract of Paeonia lactiflora and Paeoniflorin as Aggregation Reducers Targeting Chaperones in Cell Models of Spinocerebellar Ataxia 3

Spinocerebellar ataxia (SCA) types 1, 2, 3, 6, 7, and 17 as well as Huntington's disease are a group of neurodegenerative disorders caused by expanded CAG repeats encoding a long polyglutamine (polyQ) tract in the respective proteins. Evidence has shown that the accumulation of intranuclear and...

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Autors principals: Chang, Kuo-Hsuan, Chen, Wan-Ling, Lee, Li-Ching, Lin, Chih-Hsin, Kung, Pin-Jui, Lin, Te-Hsien, Wu, Yi-Ci, Wu, Yih-Ru, Chen, Yi-Chun, Lee-Chen, Guey-Jen, Chen, Chiung-Mei
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596917/
https://ncbi.nlm.nih.gov/pubmed/23533486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/471659
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