Localization of a bidirectional DNA replication origin in the native locus and in episomally amplified murine adenosine deaminase loci.

Gene amplification is frequently mediated by the initial production of acentric, autonomously replicating extrachromosomal elements. The 4,000 extrachromosomal copies of the mouse adenosine deaminase (ADA) amplicon in B-1/50 cells initiate their replication remarkably synchronously in early S phase...

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Библиографические подробности
Опубликовано в: :Mol Cell Biol
Главные авторы: Carroll, S M, DeRose, M L, Kolman, J L, Nonet, G H, Kelly, R E, Wahl, G M
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 1993
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8474455/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.5.2971
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