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IL-10 deficiency blocks the ability of LPS to regulate expression of tolerance-related molecules on dendritic cells

Interleukin-10 (IL-10) is an anti-inflammatory cytokine that plays an important role in regulating the local inflammatory immune response, but regulatory mechanisms of this cytokine have not been fully elucidated. Here, we demonstrate that IL-10 deficiency renders LPS treatment ineffective in regula...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Fang, Ciric, Bogoljub, Li, Hongmei, Yan, Yaping, Li, Ke, Cullimore, Melissa, Lauretti, Elisabetta, Gonnella, Patricia, Zhang, Guang-Xian, Rostami, Abdolmohamad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596886/
https://ncbi.nlm.nih.gov/pubmed/22622800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141733
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