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A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function

A common synonymous single nucleotide polymorphism in exon 12 of the low-density lipoprotein receptor (LDLR) gene, rs688, has been associated with increased plasma total and LDL cholesterol in several populations. Using immortalized lymphoblastoid cell lines from a healthy study population, we confi...

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Autors principals: Gao, Feng, Ihn, Hansel E., Medina, Marisa W., Krauss, Ronald M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596853/
https://ncbi.nlm.nih.gov/pubmed/23297366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds559
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