Medroxyprogestogen enhances apoptosis of SKOV-3 cells via inhibition of the PI3K/Akt signaling pathway

We sought to assess the effect of progestin on the apoptosis of epithelial ovarian cancer cell line SKOV-3 and via regulation of phosphorylation signaling in. Epithelial ovarian cancer cell line SKOV-3 was treated with medroxyprogestogen, phosphatidylinositol 3-kinase inhibitor LY294002 and vehicle...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Li, Yan, Jiang, Yi, Wan, Yicong, Zhang, Lin, Tang, Weiwei, Ma, Jingjing, Wu, Shan, Cheng, Wenjun
Format: Artigo
Langue:Inglês
Publié: Editorial Department of Journal of Biomedical Research 2013
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596754/
https://ncbi.nlm.nih.gov/pubmed/23554793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.27.20120051
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