Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation.

Cyclic AMP (cAMP)-dependent protein kinase A (PKA) stimulates the transcription of many eucaryotic genes by catalyzing the phosphorylation of the cAMP-regulatory element binding protein (CREB). Conversely, the attenuation or inhibition of cAMP-stimulated gene transcription would require the dephosph...

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Main Authors: Wadzinski, B E, Wheat, W H, Jaspers, S, Peruski, L F, Lickteig, R L, Johnson, G L, Klemm, D J
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC359667/
https://ncbi.nlm.nih.gov/pubmed/8386317
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