Deferasirox (ICL670A) effectively inhibits oesophageal cancer growth in vitro and in vivo

BACKGROUND AND PURPOSE: Growing evidence implicates iron in the aetiology of gastrointestinal cancer. Furthermore, studies demonstrate that iron chelators possess potent anti-tumour activity, although whether iron chelators show activity against oesophageal cancer is not known. EXPERIMENTAL APPROACH...

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Detalhes bibliográficos
Main Authors: Ford, SJ, Obeidy, P, Lovejoy, DB, Bedford, M, Nichols, L, Chadwick, C, Tucker, O, Lui, GYL, Kalinowski, DS, Jansson, PJ, Iqbal, TH, Alderson, D, Richardson, DR, Tselepis, C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers with Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596639/
https://ncbi.nlm.nih.gov/pubmed/23126308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12045
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