Ceramide from sphingomyelin hydrolysis differentially mediates mitogen-activated protein kinases (MAPKs) activation following cerebral ischemia in rat hippocampal CA1 subregion()

OBJECTIVE: To explore the role that ceramide plays in the activation of mitogen-activated protein kinases (MAPKs) during cerebral ischemia and reperfusion. METHODS: Rats were subjected to ischemia by the four-vessel occlusion (4-VO) method. The sphingomyelinase inhibitor TPCK was administered to the...

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Библиографические подробности
Главные авторы: Sun, Xian, Liu, Chao, Qian, Min, Zhao, Zhenghong, Guo, Jun
Формат: Artigo
Язык:Inglês
Опубликовано: Editorial Department of Journal of Biomedical Research 2010
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596547/
https://ncbi.nlm.nih.gov/pubmed/23554623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1674-8301(10)60021-8
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