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Transdermal Delivery of Molecules is Limited by Full Epidermis, Not Just Stratum Corneum

PURPOSE: Most methods to increase transdermal drug delivery focus on increasing stratum corneum permeability, without addressing the need to increase permeability of viable epidermis. Here, we assess the hypothesis that viable epidermis offers a significant permeability barrier that becomes rate lim...

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Bibliographic Details
Main Authors: Andrews, Samantha N., Jeong, Eunhye, Prausnitz, Mark R.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596453/
https://ncbi.nlm.nih.gov/pubmed/23196771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0946-7
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