Mapping of the IRF8 gene identifies a 3’ UTR variant associated with risk of chronic lymphocytic leukemia but not other common non-Hodgkin lymphoma subtypes

BACKGROUND: Our genome-wide association study (GWAS) of chronic lymphocytic leukemia (CLL) identified 4 highly-correlated intronic variants within the IRF8 gene that were associated with CLL. These results were further supported by a recent meta-analysis of our GWAS with two other GWAS of CLL, suppo...

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Hauptverfasser: Slager, Susan L., Achenbach, Sara J., Asmann, Yan W., Camp, Nicola J., Rabe, Kari G., Goldin, Lynn R., Call, Timothy G., Shanafelt, Tait D., Kay, Neil E., Cunningham, Julie M., Wang, Alice H., Weinberg, J. Brice, Norman, Aaron D., Link, Brian K., Leis, Jose F., Vachon, Celine M., Lanasa, Mark C., Caporaso, Neil E., Novak, Anne J., Cerhan, James R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596428/
https://ncbi.nlm.nih.gov/pubmed/23307532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-1217
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