The Protective Effect of Intrasplenic Transplantation of Ad-IL-18BP/IL-4 Gene-Modified Fetal Hepatocytes on ConA-Induced Hepatitis in Mice

BACKGROUND: Concanavalin A (ConA)-induced hepatitis is an experimental murine model mirroring the pathology of human autoimmune hepatitis. AIM: To investigate the effects of intrasplenically transplanted fetal hepatocytes (BNL.CL2) transfected with recombinant adenovirus vector expressing the IL-18...

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Main Authors: Shao, Xueting, Qian, Yun, Xu, Chenhuai, Hong, Bo, Xu, Wanhong, Shen, Ling, Jin, Changzhong, Wu, Zhigang, Tong, Xiangmin, Yao, Hangping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596329/
https://ncbi.nlm.nih.gov/pubmed/23516562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058836
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