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Sparse Principal Component Analysis for Identifying Ancestry-Informative Markers in Genome Wide Association Studies
Genomewide association studies (GWAS) routinely apply principal component analysis (PCA) to infer population structure within a sample to correct for confounding due to ancestry. GWAS implementation of PCA uses tens of thousands of SNPs to infer structure, despite the fact that only a small fraction...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596262/ https://ncbi.nlm.nih.gov/pubmed/22508067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21621 |
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