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Positive and negative regulation of immunoglobulin gene expression by a novel B-cell-specific enhancer element.

A new B-cell-specific enhancer element has been identified 3' of E4 and the octamerlike motifs in the human immunoglobulin heavy-chain gene enhancer. Tandem copies of this 67-bp MnlI-AluI fragment, when fused to the chloramphenicol acetyltransferase gene driven by the conalbumin promoter, stimu...

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Detalhes bibliográficos
Main Authors: Wang, J, Oketani, M, Watanabe, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC359591/
https://ncbi.nlm.nih.gov/pubmed/1986254
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