Interaction between NF-kappa B- and serum response factor-binding elements activates an interleukin-2 receptor alpha-chain enhancer specifically in T lymphocytes.

We find that a short enhancer element containing the NF-kappa B binding site from the interleukin-2 receptor alpha-chain gene (IL-2R alpha) is preferentially activated in T cells. The IL-2R alpha enhancer binds NF-kappa B poorly and is only weakly activated by the NF-kappa B site alone. Serum respon...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kuang, A A, Novak, K D, Kang, S M, Bruhn, K, Lenardo, M J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8455627/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.4.2536-2545.1993
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