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Cell cycle-dependent variations in deoxyribonucleotide metabolism among Chinese hamster cell lines bearing the Thy- mutator phenotype.

Deoxyribonucleotide pool imbalances are frequently mutagenic. We have studied two Chinese hamster ovary cell lines, Thy- 49 and Thy- 303, that were originally characterized by M. Meuth (Mol. Cell. Biol. 1:652-660, 1981). In comparison with wild-type CHO cells, both lines have elevated dCTP/dTTP rati...

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Publicat a:Mol Cell Biol
Autors principals: Mun, B J, Mathews, C K
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359580/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986219/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.1.20-26.1991
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