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Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor.

The intracellular basic region/helix-loop-helix (bHLH) dioxin receptor mediates signal transduction by dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) and functions as a ligand-activated DNA binding protein directly interacting with target genes by binding to dioxin response elements. Here we show that...

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Detalhes bibliográficos
Main Authors: Whitelaw, M, Pongratz, I, Wilhelmsson, A, Gustafsson, J A, Poellinger, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC359572/
https://ncbi.nlm.nih.gov/pubmed/8384309
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