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Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2.

The product of the c-myc proto-oncogene is an important positive regulator of cell growth and proliferation. Recently, c-Myc has also been demonstrated to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. To further examine Myc-induced apoptosis, we coexpress...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Wagner, A J, Small, M B, Hay, N
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359564/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8455620/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.4.2432-2440.1993
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