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Distinct regions of the human granulocyte-colony-stimulating factor receptor cytoplasmic domain are required for proliferation and gene induction.

Using two different cell systems, we show that the cytoplasmic domain of the granulocyte-colony-stimulating factor receptor (G-CSFR) may be composed of at least two functional regions. The first, within the membrane-proximal 57 amino acids, is absolutely required to deliver a proliferative signal. T...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Ziegler, S F, Bird, T A, Morella, K K, Mosley, B, Gearing, D P, Baumann, H
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359559/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7681146/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.4.2384-2390.1993
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