Distinct regions of the human granulocyte-colony-stimulating factor receptor cytoplasmic domain are required for proliferation and gene induction.

Using two different cell systems, we show that the cytoplasmic domain of the granulocyte-colony-stimulating factor receptor (G-CSFR) may be composed of at least two functional regions. The first, within the membrane-proximal 57 amino acids, is absolutely required to deliver a proliferative signal. T...

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Autori principali: Ziegler, S F, Bird, T A, Morella, K K, Mosley, B, Gearing, D P, Baumann, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC359559/
https://ncbi.nlm.nih.gov/pubmed/7681146
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