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Functional Profiling Discovers the Dieldrin Organochlorinated Pesticide Affects Leucine Availability in Yeast

Exposure to organochlorinated pesticides such as dieldrin has been linked to Parkinson’s and Alzheimer’s diseases, endocrine disruption, and cancer, but the cellular and molecular mechanisms of toxicity behind these effects remain largely unknown. Here we demonstrate, using a functional genomics app...

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Detalhes bibliográficos
Main Authors: Gaytán, Brandon D., Loguinov, Alex V., Lantz, Stephen R., Lerot, Jan-Michael, Denslow, Nancy D., Vulpe, Chris D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595527/
https://ncbi.nlm.nih.gov/pubmed/23358190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft018
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