Rapid decrease in tumor perfusion following VEGF blockade predicts long-term tumor growth inhibition in preclinical tumor models

Vascular endothelial growth factor (VEGF) is a key upstream mediator of tumor angiogenesis, and blockade of VEGF can inhibit tumor angiogenesis and decrease tumor growth. However, not all tumors respond well to anti-VEGF therapy. Despite much effort, identification of early response biomarkers that...

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Библиографические подробности
Главные авторы: Eichten, Alexandra, Adler, Alexander P., Cooper, Blerta, Griffith, Jennifer, Wei, Yi, Yancopoulos, George D., Lin, Hsin Chieh, Thurston, Gavin
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Netherlands 2012
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595479/
https://ncbi.nlm.nih.gov/pubmed/23238831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9328-3
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